What is Acanthopanax

Acanthopanax acanthopanax is a medicinal plant from the East Asian cold conifer forest (such as China, Russia, Japan), and the common ginseng, American ginseng is the same acanthopanax family, but the drug is slightly different.

The main active ingredients are saponins, lignans, polysaccharides, flavonol-phenolic acids, triterpenoid acids and anthocyanins, and the leaves are classified as food, and are also used as tea, soup, wine and other purposes.

Acanthophyllum acanthophyllum cuticle root and stem tissue parts are often made into tinctures or capsules, which have a variety of pharmacological effects, including anti-fatigue, improving learning, enhancing vitality, anti-inflammatory, enhancing immune and antidepressant effects, and neuroprotection, but up to now, the relevant scientific literature is still limited.

Acanthopanax, also known as Siberian ginseng, is regarded as an adaptogen in traditional medicine, meaning that it can regulate physiological functions and help fight physical or psychological stress. Acanthopanax has been used in Eastern folk medicine for thousands of years, bringing beneficial effects on physical and mental stress, fatigue, chronic bronchitis, ischemic heart disease, stomach ulcers and allergic reactions.

What are the effects of Acanthopanax

Acanthopanax acanthopanax has beneficial cognitive function

As portable media devices such as smartphones become more prevalent in our lives, they are also increasingly capable of supplementingand even replacing various cognitive functions, serving as phone books, appointment calendars, Internet portals, calculators, maps, gaming devices, and more, which can seemingly perform almost unlimited cognitive activities for us and satisfy our many emotional needs.

But relying on smartphones and related technologies does not help our cognitive function and, instead, negatively affects our ability to think, remember, pay attention, and regulate emotions.

A randomized, double-blind placebo-controlled study of 40 healthy women aged 20 to 68 years showed that ADAPT-232 extract (containing rhodiola rosea, schisandra chinensis, and Acanthopanax acanthopanax) improved attention, speed, and accuracy in stressful situations compared to a placebo.

Acanthopanax acanthopanax beneficial exercise performance

Numerous studies conducted over the last 40 to 50 years have consistently shown that carbohydrates are the primary macronutrient for maintaining and improving body function.

Carbohydrate intake is used by athletes to provide a fuel base to improve athletic performance, support the immune system, and improve the bioavailability of other supplements, such as protein supplements.

A double-blind, randomized, placebo-controlled study (8 weeks of 9 men undergoing cycling trials) showed that oral acanthopanax increased endurance, improved cardiovascular function, and altered glycogen metabolism.

Acanthopanax acanthopanax has osteoporosis

Osteoporosis is a bone disease characterized by reduced bone mass and degradation of the microstructure of bone tissue, resulting in reduced bone tone and strength and an increased risk of brittle fractures.

Proximal hip fractures, which account for about 20% of all osteoporotic fractures, are the most devastating and are associated with an additional mortality rate of 8% to 36% over a one-year period, higher in men than in women.

A randomized controlled trial (6 months of 81 postmenopausal women with osteoporosis or osteopenia) showed that taking Acanthopanax extract combined with calcium tablets increased serum osteocalcin levels (but did not show significant changes in bone mineral density) compared with a control group receiving calcium tablets.

Acanthopanax is beneficial for knee osteoarthritis

Osteoarthritis is a degenerative joint disease that involves cartilage and its surrounding tissues. In addition to damage and loss of articular cartilage, there is remodeling of the bone under the joint, osteophyte formation, ligament relaxation, weakening of the muscles around the joint, and in some cases synovial inflammation.

The main symptoms include joint pain, stiffness and limited movement, and the disease usually progresses slowly but eventually leads to joint failure.

A randomized, double-blind, placebo-controlled 7-week study of 57 patients with knee osteoarthritis showed that an anti-inflammatory factor formulation containing acanthopanax, notoginseng, and rehmannia helped improve pain and knee function as measured by the visual analog VAS and K-WOMAC scale.

Acanthopanax is beneficial for familial Mediterranean fever

Familial Mediterranean fever is an inherited autoinflammatory disease characterized by acute fever and serous membrane inflammation that primarily affects people of Eastern Mediterranean descent (most commonly Jews, Armenians, Turks, and Arabs).

The disease is associated with a mutation in the MEFV gene that codes for pyrin, which leads to an increased inflammatory response through uncontrolled production of interleukin.

Untreated or inadequately treated patients are at risk for amyloidosis, which is a significant cause of morbidity and mortality.

A one-month, double-blind, randomized, placebo-controlled study of 24 patients with familial Mediterranean fever indicated that ImmunoGuard formulations containing Acanthopanax, Andropanax androgensis, schisandra schisandra and Glycyrrheus glabripensis were helpful in improving the duration, frequency and severity of symptoms.

Acanthopanax is good for bipolar disorder, also known as bipolar disorder

Bipolar disorder is a severe psychiatric condition that is highly recurrent and disabling, often with periodic periods of high or low mood

The main symptoms include excessive talk, increased activity, risk-taking behavior, impulsive performance, etc., and severe depressive symptoms of depression, such as untreated, not only cause impaired life function, but also increase the rate of self-harm and suicide, resulting in heavy family and social burden.

A 6-week, double-blind, controlled study of 76 adolescents with bipolar disorder compared acanthopanax plus lithium with group A and fluoxetine plus lithium with group B. The results showed that the response rate and remission rate of the two groups were similar, 67.6% vs 71.8% and 51.4% vs 48.7%, respectively, while the adverse reactions were less in group A combined with Acanthopanax, and the tolerance was better.

Acanthopanax is good for chronic fatigue

Chronic fatigue syndrome (CFS) is characterized by unexplained, severe fatigue without any underlying physical condition that cannot be improved by rest.

Although the cause is unknown, the medical community believes that it may be related to viral infections or psychological stress, and may be triggered by a variety of factors, millions of people in the United States alone, women are twice as likely as men (it is common after the age of 40), and most are undiagnosed.

A controlled study (a 2-month study involving 96 patients with chronic fatigue syndrome) suggested that taking Acanopanax may have a partial relief effect on mild fatigue, but the experimental design was not precise enough and the sample size was too small to be further verified by more studies.

Acanthopanax acanthopanax is beneficial to the quality of life of the elderly

Due to the improvement of medical standards and the decline in birth rate, most advanced countries are facing the phenomenon of an aging society with an aging population. With the increase of the elderly population, there will be chronic diseases for the elderly and the increasing demand for elderly care.

In the care of the elderly, the promotion of healthy life is an important concept, which means that for the elderly with chronic diseases, the implementation of a healthy lifestyle can not immediately cure the disease, but can reduce symptoms, increase the ability to adapt to the body and mind, and reduce the resistance of the aging process.

A small, double-blind controlled study (8 weeks of 20 older adults) found that Acanthopanax helped improve participants’ scores on measures of mental health and social functioning (70% of Acanthopanax group rated the prescription as effective, compared with 20% of placebo group, but the differences between the two groups gradually decreased with continued use).

Acanthopanax acanthopanax is beneficial to the quality of life of the elderly

reference

1、Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials

2、Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions

3、The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human

4、The effects of Acanthopanax senticosus extract on bone turnover and bone mineral density in Korean postmenopausal women

5、Effects of AIF on Knee Osteoarthritis Patients: Double-blind, Randomized Placebo-controlled Study

6、Clinical effect of a polysaccharide-rich extract of Acanthopanax senticosus on alcohol hangover

7、Comparison of the Addition of Siberian Ginseng (Acanthopanax senticosus) Versus Fluoxetine to Lithium for the Treatment of Bipolar Disorder in Adolescents: A Randomized, Double-Blind Trial

8、Randomized controlled trial of Siberian ginseng for chronic fatigue

9、Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial

10、The effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal women

Andy

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