What does salvianolic acid B do
Salvianolic acid
Salvianolic acid extract can prevent acute liver injury caused by tripterygium glycosides.
Salvianolic acid extracts can regulate metabolic pathways, including sterol metabolism, lipid regulation and bile acid homeostasis pathways.
Salvianolic acid extract upregulates FXR and downstream signaling, thereby regulating bile acid metabolism and preventing acute liver injury.
Source: It was obtained from the roots and rhizomes of Salvia miltiorrhiza Bunge.
● Properties: brown dry powder
● Detection method: HPLC
● Specifications: > 5%, > 10%, > 50%, > 70%, > 90%, 98%
Pharmacological action
Antioxidant
Salvianolic acid B has a strong antioxidant effect. In vivo and in vitro experiments have proved that salvianolic acid B can clear oxygen free radicals and inhibit lipid peroxidation, and its effect intensity is higher than that of vitamin C, vitamin E and mannitol. It is one of the natural products with the strongest antioxidant effect known at present.
Protect the heart
1 Protective effect on myocardial ischemia-reperfusion injury
2. Delayed protective effect on cardiac microvascular endothelial cells
3. Prevention and treatment of atherosclerosis
4 Effect on apoptosis
5 Preconditioned cardiac cell protection.
Protective brain
1 Protective effect on cerebral ischemic injury
2. Influence on learning and memory function
antifibrosis
Salvianolic acid B can inhibit TGF-I HSC intracellular signal transduction and the expression of its receptor protein, thus antagonizing TGF-B1 to promote HSC activation, and inhibit the proliferation of activated FSC, inhibit the formation of extracellular matrix by FSC, and reduce the deposition of collagen fibers in the liver. Other studies have shown that magnesium salvianolic acid B salt has the effect of anti-lipid peroxidation and anti-liver damage, and has the function of reducing the degree of liver fibrosis, and has achieved satisfactory results in the clinical treatment of chronic hepatitis B liver fibrosis.
Anti-aging, anti-tumor
Salvianolic acid B can not only protect nerve cells through antioxidant effect, but also improve the toxic effect of J3-amyloid protein on neurons by reducing the release of NO, and enhance the aging red blood cells and increase the secretion of IL-238 by T lymphocytes, which has anti-aging and anti-tumor effects.
Other role
In addition, salvianolic acid B can also be used to prevent or treat nephritis, kidney failure, vasculitis, venous embolism, senile dementia disease, anti-aging and so on.
Salvianolic acid B has the effect of activating blood circulation and removing blood stasis, activating channels and collaterality, treating ischemic stroke caused by blocking meridians due to blood stasis. The symptoms are numbness, weakness, clonus pain, movement paralysis, mouth and eyes askew, etc.
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