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Description

Cyanocobalamin, Hydroxocobalamin, Adenosylcobalamin, and Methylcobalamin

Vitamin B12 is the general name for vitamin B family chemical substances with a cobaltine ring structure. Since cyanocobalamin was first discovered, it was ranked 12th in the naming order of vitamins, so it is called vitamin B12. It is generally customary to refer to cyanocobalamin as vitamin B12.

In fact, there are four types of vitamin B12 family: cyanocobalamin, hydroxocobalamin, adenosylcobalamin and methylcobalamin. The latter three are drugs with similar chemical structures to cyanocobalamin.

The chemical structure of the vitamin B12 family is that four pyrrole rings are connected in a bridging manner, and a 6-valent cobalt ion is complexed in the center. Different functional groups are connected to the 13th position to form different cobalamins, and the cyanide radical is connected to cyanide. Cobalamin, linked to the methyl group is methylcobalamin, linked to the hydroxyl group is hydroxocobalamin, and linked to the adenosyl group is adenosylcobalamin (see Figure 1 for the molecular structure formula).

Among them, methylcobalamin and adenosylcobalamin have direct biological activity and can directly participate in biochemical reactions in the body; while cyanocobalamin and hydroxocobalamin have no direct biological activity and need to be converted into methylcobalamin and adenosylcobalamin. exert biological activity.

Product Name	Cyanocobalamin
CAS No.	68-19-9
Appearance	Light red needle-like crystals powder
Specifications	Cyanocobalamin
Pakage	1kg/bag, 25kg/drum
Storage	Moisture-roof and avoid light, sealed storage.
Test Method	IR

Cyanocobalamin Benefits

Cyanocobalamin can participate in the synthesis of nucleic acids in the body, and can participate in the metabolism of proteins and fats. It can also maintain the integrity of the central and peripheral myelinated nerve fiber functions, and can also convert 5-methyltetrahydrofolate into tetrahydrofolate. Folic acid can also convert homocysteine into methionine and promote the conversion of methylmalonic acid into succinic acid, thus participating in the tricarboxylic acid cycle.

Cyanocobalamin is an important coenzyme for cells to synthesize nucleic acids. It can participate in the synthesis of nucleic acids in the body, and can participate in the metabolism of proteins and fats. It can also maintain the integrity of the central and peripheral myelinated nerve fiber functions, such as the formation of outer nerve fibers. The myelin protein of myelin can also convert 5-methyltetrahydrofolate into tetrahydrofolate, thereby increasing the utilization of tetrahydrofolate in the human body.

It can also convert homocysteine into methionine. In addition, it can promote the conversion of methylmalonic acid into succinic acid, thereby participating in the tricarboxylic acid cycle. When the human body lacks this substance, the circulation and utilization of tetrahydrofolate will be hindered, thymidine deoxyribonucleotide synthesis will be sharply reduced, DNA synthesis will be limited, and the maturation and division of red blood cells will stop, resulting in megaloblastic anemia.

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