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Description

Arbutin is also divided into three types: beta-arbutin, alpha-arbutin and deoxyarbutin. These three effects on the skin can be very different.

Deoxyarbutin has the best inhibitory effect on tyrosinase activity, and its anti-melanin effect is 10 times that of hydroquinone, 150 times that of kojic acid, 350 times that of β-arbutin, and 38.5 times that of α-arbutin.

Alpha Arbutin Introduction

α Arbutin, White crystal powder, easily soluble in water,methanol,ethanol,propylene glycol, glycerin without precipitates. Alpha Arbutin also known as 4-Hydroxyphenyl-alpha-D-glucopyranoside, is mainly used to bind to tyrosinase of melanocytes in the skin and inhibit tyrosinase activity. It’s a popular whitening agent in Japan and other asian countries. It mainly use in cream,essence,facial mask for whiten skin and frechles removal. And the ability of α-arbutin to inhibit this enzyme ( whitening effect) is 10 to 15 times than of β-arbutin.

Product Name	Alpha Arbutin
CAS No	84380-01-8
Latin name	Vacciniumvitis-idaeaL.
Appearance	White powder
Specifications	99.5%
Pakage	1kg/bag, 25kg/drum
Storage	Moisture-roof and avoid light, sealed storage.
Test Method	HPLC

*Hydroquinone detection value ≤1.00ppm in line with the European standard has not been detected

Why choose us Reason 1

*Color stability is excellent, will not be due to long time to yellow.

Why choose us Reason 2

arbutin

The whitening Mechanism of Alpha Arbutin

The content and distribution of melanin are the main factors that determine the depth of skin color. Melanin is produced in melanocytes in the basal layer of the skin epidermis. It is finally formed from tyrosine under the action of tyrosinase through a series of complex biochemical reactions. It is transferred from the basal layer to the outer layer of the epidermis from the inside out through synapses. Color the skin.

Tyrosinase has tyrosine hydroxylase activity (catalyzing tyrosine to produce dopa) and dopa oxidase activity (catalyzing dopa to produce dopaquinone). In the process of melanin formation, it serves as the main rate-limiting enzyme. Its activity determines the amount of melanin formed.

Arbutin is a tyrosinase inhibitor that can effectively inhibit tyrosinase activity without affecting cell proliferation concentration. It competes for the binding of dopa through its direct binding to tyrosinase. site, blocks the synthesis of dopa and dopaquinone, thereby interfering with melanocytes and inhibiting the production of melanin. At the same time, it also has the function of diluting formed melanin, accelerating the decomposition and excretion of melanin, reducing skin pigmentation, and removing spots and freckles.

Mainly Specifications of Alpha Arbutin

Alpha Arbutin crystal powder 98% HPLC
Alpha Arbutin crystal 99.5% HPLC

Benefits of Alpha Arbutin

α Arbutin acts as a whitening agent to reduce melanin in the skin.
α Arbutin can tighten pores and skin,it can also promote cell growth and help skin wounds heal.
α Arbutin also regard as antiseptic and anti-inflammatory ingredients.

Specification (TDS) of α-Arbutin

Analysis Items	Specifications	Methods
Active Ingredients Tests
α-Arbutin	≥99.5%	HPLC
Hydroquinone	≤1.00ppm	HPLC
Physical Tests
Appearance	White Crystal Powder	Visual
Particle size	90% pass 60mesh	Ch.P 2020 IV<0982>
Melting Point	202.0~210.0 ±0.5 ℃	Ch.P 2020 IV<0612>
Specific Optical Rotation	+174.0˚~+186.0˚	Ch.P 2020 IV<0621>
pH value (1% solution)	5.0~7.0	Ch.P 2020 IV<0631>
Water contents	≤0.5%	GB 5009.3
Total ash	≤0.5%	GB 5009.4
Chemical Tests
Heavy Metals	≤50.00ppm	GB 5009.11
Arsenic <As>	≤3.00ppm	GB 5009.11
Lead <Pb>	≤5.00ppm	GB 5009.12
Cadmium<Cd>	≤2.00ppm	GB 5009.15
Mercury <Hg>	≤1.00ppm	GB 5009.17
Microbiological Tests
Total Bacteria Counts	≤300cfu/g	GB 4789.2
Yeast and Molds	≤10cfu/g	GB 4789.15
Coliforms	≤90MPN/100g	GB 4789.3
Salmonella	Negative	GB 4789.4
Staphylococcus aureus	Negative	GB 4789.10
Shigella	Negative	GB 4789.5

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