Rare ginsenosides Rg3（ginsenoside rg3） unlock efficient advanced anti-aging

진세노사이드 혜택

Ginseng ginsenoside must be everyone will not feel very strange, in the major domestic TV series and martial arts novels can see the description of ginseng, ginseng is considered to be an emergency medicine of life, the reason why ginseng will have such a good therapeutic effect, it is because ginseng contains a special component, that is, life saponin. Ginsenosides are found only in the ginseng genus, and taking medicines containing ginsenosides can quickly restore energy and fight disease.

Saponins, also known as saponins, are a class of complex compounds, a special class of glycosides found in the plant kingdom, whose aqueous solution can be shaken to produce long-lasting soap-like foam, hence the name. According to the structure of saponins produced by hydrolysis of saponins, it can be divided into triterpenoid saponins and steroid saponins. The common sugars of saponins are glucose, galactose, rhamnose, arabinose, xylose, glucuronic acid, galacturonic acid, etc., which are often linked to the -OH of saponin C3 to form glycosides. Ginsenoside is a kind of sterol compound, triterpenoid saponin. Chinese scientists have found more than 200 monomer saponins from ginseng, and nearly 50 kinds of monomer saponins can be isolated from ginseng. At present, ginsenosides separated and refined by scientific and advanced technology, named Ro, Ral, Ra2, ginsenoside rb1（rb1 ginsenoside）, Rb2, Rb3, Rc, Rd, Rf, ginsenoside rg1, Rg2, rg3 ginsenoside, Rh1, Rh2, I, K, O-glaco, are composed of glycosides and sugars, except that the aglycone of Ro is oleanic acid. The others are propanaxanediol and propanaxantriol. In addition to ginseng saponins, ginseng also contains ginseng polysaccharide, ginseng protein, ginseng volatile oil, amino acids, inorganic elements, peptides, vitamins, organic acids, alkaloids, fats, flavonoids, enzymes, sterols, nucleosides, lignin and other substances. Some monomeric saponins in ginsenosides, such as Rb1, Rb2, Rd, Rc, Re, Rg1, Rg2, Rh1, can reduce the content of free radicals in vivo to varying degrees. Ginsenosides can delay the senescence of nerve cells and reduce the memory damage in old age, and can stabilize the membrane structure and increase protein synthesis, which can improve the memory ability of the elderly. Monomonosides Rg1 and Rb1 in ginseng are the main components of brain function in ginseng. Pharmacological experiments showed that ginsenosides Rg1 and Rb1 can promote the physical development of young mice, and facilitate the process of memory acquisition by jumping platform method and dark avoiding method in adult mice. Rb1 and Rg1 can significantly increase the number of synapses in CA3 region of hippocampus. This is the histomorphological basis of ginsenoside promoting learning and memory. Ginsenoside Rd, which can enhance human immunity and inhibit the growth of cancer cells, can protect cell membranes and prevent cell aging, dilate blood vessels, reduce blood pressure and blood sugar, and improve protein and DNA synthesis in liver cells.

The main effects of ginsenosides

Inducing apoptosis of cancer cells

Apoptosis is an active physiological process, just like flowering and falling of flowers. Under normal circumstances, there is always a dynamic balance between cell proliferation and apoptosis, which can maintain the normal and stable proliferation of cells. When a certain factor causes uncontrolled cell proliferation and cell apoptosis is blocked, it can lead to abnormal cell proliferation and cancer.

Enhance body immunity

One of the main causes of cancer is the dysfunction or low immune function of the human body. Chemotherapy drugs or radiation therapy used in cancer treatment can further destroy the body’s immune function. Ginsenoside alone can effectively regulate human immune function. It can effectively protect immune organs and enhance immune function when used in combination with radiotherapy and chemotherapy after operation.

Boost immunity

Immunity is its own natural defense barrier, immune disorders, then the immune surveillance function is lost, can not clear mutated cells, is also one of the causes of tumor. Ginsenoside rh2 can regulate and enhance the immunity of the body through various ways, and has a protective effect on the immune system.

Toxin relieving effect

In the process of treating tumor, it is found that the failure of cancer chemotherapy is often related to the resistance of chemotherapy drugs. General chemotherapy drugs are not easy to enter cancer cells, and P-glycoprotein in cancer cells can discharge chemotherapy drugs, resulting in poor resistance of cancer cells to chemotherapy drugs. Ginsenosides have two characteristics: hydrophilic and lipophilic, and can easily enter the nucleus of cancer cells to kill cancer cells.

Anti-fatigue effect

Ginsenosides can prolong the weight-bearing swimming time of mice, increase the glycogen reserve or reduce the glycogen consumption of mice, reduce the serum urea content of mice after exercise, and inhibit the increase of blood lactic acid of mice after exercise, indicating that ginsenosides have a good effect on relieving physical strength and anti-fatigue.

Clinical and related application of ginsenosides

1, used in the medical and health care industry, can be prepared into anti-fatigue, anti-aging and brain health food.

2, used in the beauty and cosmetics industry, can be formulated into freckle, reduce wrinkles, activate skin cells, enhance skin elasticity of cosmetics.

3, can also be used as a food additive. Efficacy: warm, sweet taste, slightly bitter. Big tonifying vitality, strong heart solid out, calming and Shengjin.

In today’s skin care field, herbs have become a favored raw material, and their natural, gentle and unique bioactive substances have led the new trend in skin care science.

In many herbs, more “Chinese characteristics” of the Chinese herbal ingredients advantage is obvious, domestic consumers have a natural sense of affinity and trust, in recent years, ginseng, dendrobium, ganoderma, mushroom ingredients also rise, ginseng as one of the best, in the field of skin care and beauty has been widely used.

Modern pharmacological studies have shown that ginsenosides, the main chemical components of ginseng, have anti-aging, sunscreen, whitening, moisturizing, anti-inflammatory and other skin care effects in vivo and in vitro.

The prototype ginsenoginseng, the content of 4% in ginseng, can be directly extracted, but the absorption rate is low. The rare ginsenoginseng obtained by synthetic biology technology only accounts for 1/100,000 in ginseng. Its biological activity is stronger, and it is easier to be absorbed by the human body in modern medicine, skin care and other fields.

Studies have shown that rare ginsenosides can effectively improve the metabolism and transport function of mitochondrial target active substances, and can increase the expression of transporters by 30%-170%.

After fermentation, ginsenoside Rg3 content in ginseng extract was increased by 300%. Experiments showed that ginsenoside Rg3 can significantly alleviate skin photoaging, reverse photooxidation, and make skin bright and complexion.

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