Benefits of Turmeric Root Extract Curcumin

커큐민

강황 뿌리 추출물 커큐민 is a diphenylmethane polyphenol with two phenolic rings (like resveratrol) and is an active ingredient extracted from the rhizome of the tropical plant turmeric. It was first isolated by Vogel and Pelletier in 1815, and its chemical structure was determined by Lampe e Milobedeska in 1913. Curcumin in turmeric extract is the most medically valuable part, accounting for approximately 3%-5% by weight, although Not much, but it has very strong anti-inflammatory and antioxidant capabilities. Current medical research mainly uses this ingredient.

 According to a well-known American journal, the antioxidant capacity of natural curcumin is 2.33 times that of bioflavonoids, 1.6 times that of vitamin E, and 2.75 times that of vitamin C. It can help the human body fight many diseases.

강황 뿌리 추출물 커큐민 Relieve joint inflammation and pain

 One of the most common uses of curcumin is to combat joint pain and discomfort caused by arthritis. Severe arthritis symptoms include: limited movement, stiffness, and excessive swelling. As the inflammation progresses, these symptoms become more severe and, if left untreated, may cause permanent disability.

 A large number of studies have shown that curcumin can inhibit the release of inflammatory mediators related to the development of rheumatoid arthritis, psoriatic arthritis and osteoarthritis, can continuously improve arthritis symptoms, and can be used as a good supplementary treatment to relieve joint pain.

Turmeric Root Extract Curcumin Improve chronic inflammation

 Inflammation is the body’s immune system’s response to an irritant or threat. Inflamed areas often become swollen, red, or painful. While this is a normal response, sometimes the immune system gets silly. If inflammation becomes chronic, it can become a serious health problem.

 Many trials have shown that curcumin has anti-inflammatory properties by inhibiting key inflammatory markers in the body. Turmeric’s antioxidant activity also helps reduce oxidative stress, a process associated with low-grade inflammation.

Relieve low back pain

 Often, chronic low back pain results from an underlying problem, including sciatica, herniated disc, or spinal problems. While turmeric cannot directly cure these conditions, it has shown potential to control low back pain by reducing inflammation and reducing free radical damage.

Turmeric Root Extract Curcumin Help lose weight

 Obesity can lead to many health problems, such as high blood pressure, diabetes, heart disease, stroke, etc. As a healthy person, losing weight should be easy. However, for a patient with a metabolic disease, weight loss can be a little more complicated.

 Several trials have shown that curcumin can increase insulin sensitivity, regulate lipid metabolism, stabilize metabolism and manage weight by inhibiting multiple processes of adipose tissue growth.

강황 뿌리 추출물 커큐민 Improve skin health

 Skin is the most important and outermost protective layer of the body. Skin protects us from harmful microorganisms and regulates the body’s temperature. Skin diseases, such as chronic acne, eczema and psoriasis, are the second most common disease worldwide after tooth decay.

 Many people try using turmeric powder to make facial masks and other topical solutions for treating the skin. Scientists have shown that curcumin can improve inflammation by reducing oxidative stress associated with skin diseases. Turmeric can also enhance collagen synthesis and significantly speed up tissue repair.

Turmeric Root Extract Curcumin natural blood thinner

 A blood clot occurs when platelets move to and fill the injured area. This is a normal body function. If the human body does not have coagulation function, a small cut by a piece of paper will turn into a disaster. But sometimes, certain health conditions require blood thinning to prevent blood clots from forming.

Turmeric Root Extract Curcumin Improve liver function indicators

Common functions of the liver include glucose, fat, protein metabolism, coagulation function, metabolism and excretion of various substances, immune function and regeneration

 Liver function tests are used to partially evaluate liver function. Liver enzymes such as aspartate aminotransferase and alanine aminotransferase can convey information about liver cell damage, while bilirubin, albumin and international normalized ratio convey liver function information. Platelet count provides The degree of portal hypertension has different sensitivities and specificities.

 A systematic literature review and meta-analysis (including 31 randomized controlled trials with a total of 1948 adult participants) found that oral turmeric/curcumin supplementation improved liver measures, including aspartate Acid aminotransferase (AST) and alanine aminotransferase (ALT), but there is no obvious effect on γ-glutamyl transpeptidase (GGT).

*Daily doses of supplements range from 80 mg (nanocurcumin) to 3000 mg (turmeric powder), and intervention durations range from 4 to 24 weeks

 *Conclusion: Turmeric/curcumin supplements may be helpful in improving liver function indicators, but it is limited by the low quality of the existing evidence. More studies are still needed to further verify its clinical effectiveness.

 Turmeric Root Extract Curcumin Beneficial for diabetic foot ulcers (external use)

 Diabetic foot ulcers have become one of the main causes of disability and death in patients with diabetes (complications include infection and lower limb amputation). They are caused by changes in peripheral blood vessels and nerves, with a prevalence rate of 4%-10%.

 The treatment of diabetic foot ulcers includes debridement, blood sugar control, and infection prevention. Wound dressings play an indispensable role in the treatment. They can accelerate the wound healing process, inhibit the reproduction of microorganisms, and improve the wound healing rate.

 A 5-week randomized controlled trial of 76 participants with grade 3 diabetic foot ulcers found that using turmeric ointment (standardized to contain 10% curcumin) in addition to standard care helped reduce the risk of Foot ulcer area.

 *Conclusion: For diabetic foot ulcers, topical ointment containing curcumin may bring positive help.

 Turmeric Root Extract Curcumin Beneficial for migraines

 Migraine is caused by nerve and blood vessel dysfunction, with recurring pain on one or both sides of the head, often accompanied by nausea, vomiting, sound sensitivity, etc. The incidence rate is 8.4% to 28% worldwide, approximately 18.2% of women and 6.5% of men suffer from migraine.

 It can occur at any age, affecting work or school, and nearly a third of people may miss work or school because of headaches.

 Therefore, how to relieve headaches and reduce the impact on life and work has become a basic desire of many patients.

 An eight-week randomized controlled trial of 44 women with migraine found that curcumin (1,000 mg daily) reduced migraine severity and duration compared with placebo. For example, CGRP-calcitonin gene related peptide and interleukin 6 have also improved.

 *Conclusion: In women with migraine, curcumin supplementation may reduce the severity and duration of migraine attacks, but is limited by the short study duration and small sample size, and more research is needed Further verification.

 Turmeric Root Extract Curcumin Muscle damage caused by beneficial exercise

High-intensity exercise that results in repeated eccentric muscle contractions, tissue vibration, high levels of collision or impact, and involves high metabolic expenditure leading to the destruction or degradation of structural proteins in muscle fibers and connective tissue is known as exercise-induced muscle injury

Symptoms of exercise-induced muscle injury include reduced muscle strength, loss of range of motion, edema, and delayed-onset muscle soreness, which gradually decrease 5 to 7 days after exercise.

 A systematic literature review and meta-analysis (including 9 randomized controlled trials with a total of 379 exercise training participants) pointed out that curcumin supplementation has a significant effect on reducing creatine kinase and muscle soreness index.

 In addition, subgroup analyzes found that creatine kinase concentrations and muscle soreness index were significantly reduced regardless of differences in post-exercise follow-up, curcumin dose, study duration, exercise type, training status, and study design.

*Conclusion: Oral curcumin may be helpful for muscle damage and delayed onset muscle soreness caused by exercise.

 Turmeric Root Extract Curcumin Beneficial Non-Surgical Treatment for Periodontitis

 Periodontitis is a chronic disease of periodontal tissue (affecting approximately 20%-50% of the world’s population). The inflammatory response caused by different periodontal pathogens can determine the destruction of periodontal tissue, the resorption of alveolar bone, and ultimately Resulting in tooth loss.

 Periodontitis is not only a local inflammatory disease but is also associated with multiple systemic diseases, including endothelial dysfunction, diabetes, metabolic syndrome, and autoimmune diseases.

 A systematic literature review and meta-analysis (Meta-Analysis, including 14 randomized controlled trials) pointed out that compared with scaling and root planing alone (treatment), the use of curcumin as an adjuvant treatment (as an irrigant or photoantibacterial agent ), can reduce probing depth and increase clinical attachment level.

*Conclusion: For the non-surgical treatment of periodontitis, using curcumin as an adjuvant treatment may bring positive help, but more research is needed to confirm it.

 Turmeric Root Extract Curcumin Good for depression

 Depression is a mental disorder characterized by sadness, loss of interest in activities, and decreased energy. Other symptoms include loss of confidence and self-esteem, inappropriate feelings of guilt, thoughts of death and suicide, difficulty concentrating, and sleep and appetite disturbances.

 It is estimated that depression affects 350 million people worldwide.The World Mental Health Survey, conducted in 17 countries, found that on average 1 in 20 people had experienced an episode of depression in the previous year, with the direct financial cost of depression in terms of treatment costs, as well as in lost work days and reduced productivity. The indirect costs incurred are a major problem faced by public health workers.

 A systematic literature review and meta-analysis (including 6 clinical trials) pointed out that curcumin was helpful in the remission rate of depression or depression symptoms. However, there was no difference in the withdrawal rate, digestive symptoms and neurological symptoms.

*Conclusion: Limited by the low quality of the existing evidence, there is great uncertainty in the efficacy and acceptability of curcumin for depression or depressive symptoms, and more studies are needed to further verify it.

 Turmeric Root Extract Curcumin Beneficial for polycystic ovary syndrome

 Polycystic ovary syndrome is a reproductive, metabolic and hormonal disease (prevalence 6%-10%) that accounts for 50%-70% of anovulatory infertility in women of childbearing age.

 The cause of PCOS is not completely clear at present, but it may be the result of the interaction of genetic and environmental factors such as family history, low birth weight, obesity, poor eating habits, and sedentary life.

 Studies have shown that after PCOS is diagnosed, more than 50% of patients develop prediabetes or diabetes, which also increases the risk of myocardial infarction, dyslipidemia, hypertension, anxiety, depression, endometrial cancer, and sleep apnea. In addition, pregnant women with PCOS have an increased incidence of miscarriage, gestational diabetes, preeclampsia, and premature birth.

 A systematic literature review and meta-analysis (Meta-Analysis, including 3 randomized controlled trials with a total of 168 patients with polycystic ovary syndrome) pointed out that oral curcumin (dose of 500 mg to 1500 mg per day, treatment period of 6 weeks to 12 weeks) helps to improve fasting blood glucose, fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), quantitative insulin sensitivity test index (QUICKI) and total cholesterol.

*Conclusion: For patients with polycystic ovary syndrome and metabolic abnormalities, curcumin can help improve blood sugar control and lipid metabolism, but it is limited by the small sample size and more research is needed to confirm it.

 Turmeric Root Extract Curcumin Beneficial for recurrent aphthous stomatitis

Recurrent aphthous stomatitis, also known as recurrent aphthous stomatitis/oral ulcers/oral ulcers, is the most common oral disease characterized by repeated destruction of the oral mucosa, manifesting as painful ulcers

 Local trauma, genetic factors, malnutrition, viral and bacterial infections, immune or endocrine disorders are all considered to be common causes of oral ulcers.

 There are three subtypes of recurrent aphthous stomatitis: mild (>70%), severe (10%), and herpetiform (10%). These subtypes vary in morphology, distribution, severity, and prognosis, but all forms have a significant impact on quality of life and interfere with activities of daily living.

 A systematic review (including 8 studies, a total of 439 patients with recurrent aphthous stomatitis) pointed out that the use of curcumin can reduce pain and ulcer size, and the effect is not inferior to the anti-inflammatory drug triamcinolone.

The underlying mechanism may be related to the fact that curcumin inhibits inflammatory response by inhibiting phospholipase, lipase, cyclooxygenase-2 and reducing pro-inflammatory cytokines.

*Conclusion: For recurrent aphthous stomatitis, curcumin may be of positive help in relieving pain and accelerating healing, but it is limited by the small sample size and heterogeneity between studies, and more research is needed to confirm it.

 Turmeric Root Extract Curcumin Beneficial Cancer Treatment

 Cancer kills millions of people worldwide every year, and despite great advances in medicine, there are still many issues that must be addressed to improve cancer treatments.

 As a result, oncology research is focused on finding new, effective treatments that can alleviate the serious side effects of traditional treatments.

 A systematic literature review (including 22 cancer treatment studies) found that oral curcumin increased the effectiveness of chemotherapy and radiotherapy, reduced treatment-related side effects, thereby improving patient survival time and reducing tumor marker levels.

*Conclusion: Curcumin combined with cancer radiotherapy and chemotherapy may improve the effectiveness of treatment, but it is limited by the small sample size and the heterogeneity between studies. More large-scale studies are still needed for further verification.

Turmeric Root Extract

 Turmeric Root Extract Curcumin Improve health-related quality of life

 Health-related quality of life is a multidimensional concept that includes areas related to physical and motor skills, psychological status, social and economic conditions, and body perceptions (such as symptoms, especially pain). It not only directly measures population health, life expectancy and causes of death, but also focuses on the impact of health status on quality of life.

 A related concept of HRQoL is well-being, which assesses positive aspects of life such as positive emotions and life satisfaction. Clinicians and public health officials often use HRQoL to measure the impact of chronic disease, treatment effectiveness, and disability.

 A systematic literature review and meta-analysis (including 10 randomized controlled trials with a total of 730 participants) found that oral curcumin supplementation has an effect on improving health-related quality of life. Remarkable overall effect.

In addition, subgroup analysis found that the relevant improvement effects were particularly significant in trials with an intervention time of less than 5 months and those using high bioavailability formulas.

*Conclusion: Oral curcumin supplementation can have positive effects on improving health-related quality of life, but considering the heterogeneity of the included studies, more large-scale and long-term trials are still needed for further verification.

 Turmeric Root Extract Curcumin Fights oxidative stress

Oxidative stress is characterized by an imbalance in the production and elimination of reactive oxygen species, which can lead to protein carboxylation, DNA damage, cytoskeletal disruption, and lipid peroxidation, and is associated with aging and a variety of chronic diseases including cancer, lung disease, diabetes, and neurodegeneration. Sex linked to cardiovascular disease

Serum malondialdehyde, glutathione peroxidase, and superoxide dismutase activities are considered primary measures of oxidative stress

 A literature meta-analysis (including 17 randomized controlled trials) pointed out that compared with the control group, curcumin significantly reduced malondialdehyde and increased superoxide dismutase, catalase, and glutathione excess. Oxidase levels.

In addition, sub-group analysis found that curcumin could increase superoxide dismutase levels only under the action of piperonin, while curcumin could significantly reduce malondialdehyde levels regardless of whether piperonin was used in combination.

*Conclusion: Curcumin can help improve the body’s ability to resist oxidative stress, but due to the heterogeneity of the included studies, more research is still needed to confirm it.

 Turmeric Root Extract Curcumin Beneficial for blood lipid regulation

Dyslipidemia is characterized by high triglycerides, low levels of high-density lipoprotein cholesterol, and an increased proportion of low-density lipoprotein cholesterol (LDL-C) particles

Over the past few decades, statins have been the cornerstone of treatment for dyslipidemia, reducing the risk of atherosclerotic cardiovascular disease by 15% to 37%, but still causing 60% to 80% of atherosclerotic cardiovascular disease Risk exists

 A systematic literature review and meta-analysis (including 16 randomized controlled trials related to metabolic syndrome) found that turmeric and curcumin can reduce triglycerides, total cholesterol, low-density lipoprotein cholesterol, and increase high-density lipoprotein cholesterol. .

In addition, subgroup analysis showed that curcumin-related blood lipid-regulating effects were most significant when the use period was greater than 8 weeks and the daily dose was greater than 300 mg.

The mechanism behind it may be related to curcumin’s regulation of citric acid cycle, glycolysis, gluconeogenesis, synthesis of ketone bodies and cholesterol, ketogenic effect of branched-chain amino acids, choline metabolism and fatty acid metabolism.

*Conclusion: For adults with metabolic syndrome, the use of curcumin has a positive effect on blood lipid regulation. However, due to the heterogeneity of the included studies, more homogeneous and high-quality randomized controlled trials are still needed to support it.

 Turmeric Root Extract Curcumin Beneficial in blood pressure regulation

 Hypertension is part of a clinical syndrome whose etiology is multifactorial and is caused by a combination of genetic, environmental and behavioral factors that can lead to the development of complex cardiovascular disease and is estimated to affect 65% of people over the age of 60 years. affected by the disease.

Data from observational studies indicate that the risk of coronary artery disease and stroke increases gradually from 115/75 mmHg above and that mortality from both diseases doubles for every 20/10 mmHg increase in blood pressure.

 A systematic literature review and meta-analysis (including 11 randomized controlled trials with a total of 734 participants) pointed out that, overall, oral curcumin and turmeric are effective in reducing systolic blood pressure (SBP) and diastolic blood pressure (DBP). ) is of no apparent help.

 Additionally, subcohort analysis showed that significant reductions in systolic blood pressure levels, but not diastolic blood pressure, were observed in studies supplementing for ≥12 weeks.

*Conclusion: Long-term supplementation of curcumin or turmeric may have a positive effect on blood pressure regulation, but due to the small sample size and potential interfering factors, more research is needed to confirm it.

 Turmeric Root Extract Curcumin Beneficial for non-alcoholic fatty liver disease

 Non-alcoholic fatty liver disease is characterized by an accumulation of greater than 5% liver fat in the absence of any secondary cause, such as excessive alcohol consumption, viral hepatitis, Wilson’s disease, hemochromatosis, autoimmune hepatitis, bile Stasis liver disease, starvation, lipodystrophy, celiac disease, Cushing’s disease, and drug therapy (corticosteroids, methotrexate, diltiazem, oxaliplatin, amiodarone, isoniazid, highly active antiretroviral treatment, etc.)

 The global prevalence of non-alcoholic fatty liver disease is currently estimated to be as high as 1 billion, including simple steatosis and non-alcoholic steatohepatitis, which can ultimately lead to fibrosis and cirrhosis, and may progress to cirrhosis or hepatocellular carcinoma. The most important cause of cryptogenic cirrhosis.

 A literature meta-analysis (meta-analysis, including 4 randomized placebo-controlled trials, a total of 229 patients with non-alcoholic fatty liver disease) pointed out that curcumin can effectively reduce low-density lipoprotein cholesterol, triglycerides, fasting blood glucose, Insulin resistance, body weight, and aminotransferase levels.

In addition, the related benefits are not significantly helpful for total cholesterol, high-density lipoprotein cholesterol, glycated hemoglobin, alanine aminotransferase, and insulin.

*Conclusion: Oral curcumin may have a positive effect on non-alcoholic fatty liver disease, but it is limited by the small sample size and more large-scale trials are needed to confirm it.

 Turmeric Root Extract Curcumin Beneficial for oral submucosal fibrosis

Oral submucosal fibrosis is a chronic latent disease that affects the oral cavity and can involve the throat or esophagus. Mucosal fibrosis causes hardening of the oral mucosa and deep tissues, gradually leading to difficulties in eating, swallowing, and pronunciation.

The cause of this disease is unknown, but various factors that may lead to oral submucosal fibrosis include: genetic susceptibility, capsaicin, betel nut chewing, autoimmunity, hormones, and nutritional deficiencies such as vitamin B12 and iron.

 A systematic review (including 6 randomized clinical trials with a total of 298 patients with oral submucosal fibrosis) pointed out that oral curcumin can effectively relieve related symptoms and signs, especially pain or burning sensation.

 *Conclusion: Curcumin may be helpful in improving the symptoms of oral submucosal fibrosis. However, due to the small sample size and heterogeneity among studies, more accurately designed studies are needed for further verification.

Turmeric Root Extract Curcumin Increase brain-derived neurotrophic factor

 Brain-derived neurotrophic factor is a member of the neurotrophic factor family, which also includes nerve growth factor, neurotrophic factor 3 and neurotrophic factor 4

Brain-derived neurotrophic factor is one of the neurotrophic factors that supports the differentiation, maturation, morphological plasticity and survival of neurons in the nervous system. It has neuroprotective effects under adverse conditions such as glutamate stimulation, cerebral ischemia, hypoglycemia, and neurotoxicity.

Many neurodegenerative and psychiatric disorders, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, Huntington’s disease, major depression, bipolar disorder, schizophrenia, and anxiety disorders, are associated with low BDNF levels

 A systematic literature review and meta-analysis (including 4 randomized controlled trials with a total of 139 participants) reported that curcumin supplementation (daily doses ranging from 200 mg to 1820 mg, trial duration from 8 weeks to 12 weeks) ) can significantly increase serum brain-derived neurotrophic factor (BDNF) levels. Note 1

 In addition, subgroup analysis showed that the related serum BDNF level-increasing effect was particularly significant in the following subjects, such as: women, participants over 40 years old, high-dose curcumin (≥500 mg/d), and longer trials Time (>8 weeks)

*Conclusion: Supplementing curcumin can help increase brain-derived neurotrophic factor (BDNF), which may be helpful for neurological diseases related to low BDNF levels.

 Turmeric Root Extract Curcumin Beneficial for Irritable Bowel Disease

 Irritable bowel syndrome is a chronic functional gastrointestinal disorder that affects 9% to 23% of the world’s population and is typically characterized by recurrent abdominal pain associated with changes in bowel habits (diarrhea, constipation, or both) but without Detectable structural and biochemical abnormalities (eg, gastrointestinal bleeding, weight loss, fever, anemia, or abdominal mass)

Because the clinical symptoms of irritable bowel syndrome are variable and common comorbidities include: gastroesophageal reflux, genitourinary symptoms, fibromyalgia, headache, back pain, and psychological symptoms, it is often misdiagnosed initially.

 A systematic literature review and meta-analysis (Meta-Analysis, including 3 randomized controlled trials with a total of 326 patients with irritable bowel syndrome) pointed out that although curcumin is helpful in improving the symptoms of irritable bowel syndrome, the effect is not statistically significant. Significantly (compared to placebo).

*Conclusion: Oral curcumin may be helpful in improving irritable bowel syndrome. However, due to the small sample size and high heterogeneity of the included studies, more well-designed, long-term, large-scale studies are still needed to confirm its clinical effectiveness.

 강황 뿌리 추출물 커큐민 Relieve ulcerative colitis

 Ulcerative colitis, a subgroup of intestinal inflammatory diseases, is a chronic disease affecting the mucosa of the rectum and colon, affecting more than 600,000 Americans, and is caused by multiple factors such as genetic susceptibility, environmental factors, immune Dysbiosis and intestinal bacterial imbalance.

 Common symptoms include: bloody diarrhea, abdominal pain, fever, high fever, weight loss, and diffuse abdominal tenderness. The 10-year colonoscopy resection rate of patients is 9% to 24%, and the cumulative colonoscopy resection rate in 25 years is 33% to 45%.

 A systematic literature review and meta-analysis (Meta-Analysis, including 3 randomized controlled trials in patients with mild to moderate ulcerative colitis) pointed out that compared with placebo, adjuvant curcumin treatment can alleviate or improve the disease. There was no obvious clinical response.

*Conclusion: Oral curcumin has no obvious help in improving ulcerative colitis. However, due to the small sample size and high heterogeneity of the included studies, more long-term large-scale studies with precise design are still needed to confirm its clinical effectiveness.

 Turmeric Root Extract Curcumin Improve Alzheimer’s disease

Alzheimer’s disease is the most common type of dementia, accounting for about 60-70% of all cases. It mainly shows a progressive decline in memory, thinking, language and learning abilities. In the final stage, it even loses the ability to autonomously. caregiver

It is estimated that about 40 million people in the world currently suffer from this disease. However, due to the aging of the population, the number of people suffering from the disease will triple by 2050. Therefore, how to prevent it deserves attention.

 So far, although curcumin has been found to affect and inhibit the formation of Alzheimer’s disease through multiple pathways (such as antioxidant, anti-inflammatory, and inhibition of amyloid beta), most relevant studies are limited to animal and in vitro studies.

However, human studies have not yet shown the expected effects, which are generally believed to be related to difficulty in absorption, bioavailability, and the time and length of use.

However, there are currently more new patented technologies that can increase the bioavailability, blood-brain barrier penetration rate and half-life of curcumin, so future human studies need to further confirm its effectiveness.

 Turmeric Root Extract Curcumin Improve premenstrual syndrome

Premenstrual syndrome generally refers to recurring emotional and physiological symptoms during the luteal phase. Epidemiological studies have found that about 50% to 80% of women have experienced mild to moderate premenstrual discomfort symptoms.

Although premenstrual discomfort can be treated symptomatically according to the symptoms, patients are often deterred due to potential drug side effects.

 A double-blind controlled study (3 consecutive cycles, 70 women with premenstrual syndrome) showed that compared with placebo, taking curcumin (100 mg every 12 hours) before and after menstruation can help improve premenstrual symptoms. The severity of the syndrome (measured by 3 questionnaires: physical, psychological and behavioral).

 The mechanism behind it is related to curcumin’s ability to regulate neurotransmitters (serotonin, dopamine and norepinephrine) and inhibit prostaglandin production (both of which are considered to be the main factors causing premenstrual discomfort)

Turmeric Root Extract Curcumin Improve functional dyspepsia

The digestive organ is the most important function to maintain life. After eating food, all nutrient absorption depends on it. It is like the roots of a big tree, responsible for absorbing nutrients and making life thrive.

 But in this society where everything is about efficiency, even the enjoyment of life, eating, has begun to change quickly. People start to wolf down and overeat. The consequence is that not only do they not enjoy the delicious food, but they often suffer from gastrointestinal dysfunction. Imbalance, causing symptoms such as bloating, abdominal pain, belching, and heartburn.

 In medicine, these symptoms are also named functional dyspepsia, which means organic diseases such as gastrointestinal ulcers, inflammation, and tumors are ruled out after careful examination.It is estimated that among every 10 clinical patients with indigestion, 7 have functional indigestion, which has a huge impact on the quality of life of Chinese people.

 In ancient Chinese and Indian medicine, turmeric is regarded as a digestive function promoter, with antibacterial, anti-inflammatory, (stimulating bile secretion, improving fat absorption), reducing flatulence, and improving ulcer effects Note 26

 A randomized study found that after patients with indigestion took turmeric for seven consecutive days, 87% of the patients reported improvement in symptoms such as abdominal pain, flatulence, and belching (compared to 53% of the control group).

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