뇌 건강을 위한 커큐민의 4가지 중요한 이점
무엇 커큐민?
Curcumin is a bright orange-yellow compound found in turmeric, which gives curries their distinctive color (and is also often added to yellow mustard). Turmeric has been used as a prescription (grade) for thousands of years and is a revered herb in Ayurvedic medicine. Curcumin is often thought of as an anti-inflammatory prescription that can ease pain and inflammatory responses, but now it’s also finding great potential for optimizing brain health. Recent medical trials have shown that curcumin helps repair depression, anxiety and schizophrenia.
커큐민 is structurally known as a “polyphenol”. Polyphenols are widely distributed in nature and are found in many different plants. In addition to curcumin, several flavonoid-rich herbs have been studied for their potential benefits to brain health, including green tea, grape seed, and pine bark extracts. In general, polyphenols such as curcumin are strong antioxidants, which may play a health-promoting role.
커큐민 and depression
Depression is very difficult to repair, and only about 50% of patients respond to standard medications. Even in patients with optimization, it is usually only partially optimized and accompanied by significant sequelae. For the large number of patients who do not respond well to standard therapies, alternative therapies, especially those with strong reassurance, are needed.
While some other natural remedies, such as St. John’s wort and saffron, also have some healing effects on depression, the new curcumin study strongly suggests that curcumin also has some healing effects on depression and low mood. Interest in curcumin to repair depression is growing as animal models have shown that curcumin has a variety of effects, including normalization of stress response, anti-inflammatory effects, and optimization of neurotransmitter function (including serotonin).
Since 2013, scientists have been conducting medical trials of curcumin to repair depression for the past 10 years. The first medical trials used fairly low doses of curcumin and black pepper extract to enhance absorption. Patients were treated for 5 weeks with a combination of standard prescription and curcumin or placebo, as required. While the results were not significant, the trial did find that curcumin provided faster relief of symptoms than no curcumin.
Further studies explored different formulations and different dosage ranges of curcumin. A very recent meta-analysis combined the results of nine different medical trials; The results show that curcumin can optimize the symptoms of depression. The study even found that the effect size was large, indicating a strong antidepressant effect.
커큐민 and anxiety
While several natural remedies are beginning to show promise in repairing anxiety, including passion flower, lemon flower, zanthoxylum and kava pepper, medical trials of curcumin are also promising. Since many people with depression also have anxiety, many medical trials of curcumin have evaluated both depression and anxiety symptoms.
While not all trials found an anti-anxiety effect, most did. The review concluded that curcumin is helpful for both depression and anxiety.
Curcumin and Alzheimer’s disease
The most common type of dementia is Alzheimer’s disease. The disease comes on very slowly and may develop over a period of 10-20 years as damage to the brain accumulates.
The earliest symptoms include memory problems, but as the disease progresses, it can be devastating, leaving patients unable to take care of themselves or recognize friends or family.
At present, the main repair method of Alzheimer’s disease may be moderate optimization of function; However, they do not slow the progression of the underlying disease. With more and more people living with dementia worldwide, we need better prevention and repair tools now more than ever.
As with other diseases, some preliminary medical research suggests benefits from natural remedies, including fish oil, citicoline acetylcarnitine, and others. Curcumin also seems to work well in natural remedies.
Blood sugar problems and glucose metabolism disease are closely related to Alzheimer’s disease. Because of the strong association, Alzheimer’s disease has been described as a type 3 carbohydrate-metabolic disease. Curcumin has some benefits in controlling blood sugar, which is one of the drivers of glycometabolic disease.
In addition, Alzheimer’s has typical brain damage that occurs many years later, including amyloid plaques and tau tangles. Curcumin has been shown, at least in animal models, to control the formation of amyloid plaques and reduce the levels of amyloid plaques that have already formed. If these effects are also effective in humans, then curcumin is effective in both prevention and repair.
protect the cardiovascular system
Abnormal platelet aggregation tends to cause the formation of blood clots, and curcumin has been shown to prevent abnormal platelet aggregation by enhancing prostacyclin synthesis and inhibiting thrombin synthesis, thereby improving blood circulation.
At the same time, curcumin may reduce cholesterol and triglyceride levels in the body by reducing the absorption of cholesterol in the gut and increasing the conversion of cholesterol into bile acids in the liver, which can speed up the flow of blood in the cardiovascular system to protect cardiovascular health and protect the brain from the risk of blood clots.
What other properties does curcumin have?
The comfort of curcumin
Curcumin has been shown to be quite reassuring and is generally well tolerated in medical trials. However, two issues are worth highlighting. Curcumin as a supplement in the end how much effect, and a large number of human medical studies have shown that curcumin is not only good for the liver, even for liver disease is also good.
Bioavailability of curcumin
Curcumin is insoluble in water and is generally difficult to absorb in the digestive tract. Therefore, many supplements have some way of increasing absorption. Black pepper extract (piperine), nanoparticles and emulsified products are often used to improve bioavailability. In general, products with proven advantages of enhanced absorption and medical research support are recommended.
참조
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