使用のプエラリン30%、98%
Puerarin, also known as puerarin flavone, is a natural isoflavone carbon glycoside, which is the key component of puerarin to play a medicinal role. Puerarin has the functions of lowering blood sugar, regulating blood lipids, protecting blood vessels, anti-oxidative stress, anti-infection, improving insulin sensitivity index, and less adverse reactions, known as “phytoestrogen”, which is clinically used in the treatment of cardiovascular and cerebrovascular diseases, cancer, Parkinson’s disease, Alzheimer’s disease, diabetes and diabetic complications.
Source: Pueraria lobata (Willd.) Ohwi was extracted from dry roots
Properties: Brown powder
CAS Number: 3681-99-0
Molecular formula: C21H20O9
Molecular weight: 416.378
Clinical use of puerarin
Puerarin Treat diabetes
Puerarin can treat diabetes by lowering blood sugar concentration. Puerarin can up-regulate insulin receptor substrate IRS-1 and insulin-like growth factor IGF-1 protein, and promote the expression of insulin receptor InsR and peroxisome proliferator-activated receptor PPARα, so as to reduce blood sugar and treat diabetes. In addition, puerarin can also inhibit the activity of α-glucosidase, thereby reducing blood sugar concentration and achieving the purpose of treating diabetes.
Puerarin 抗腫瘍効果
Puerarin has obvious inhibitory effect on the proliferation of tumor cells, and it can promote the apoptosis of tumor cells and have therapeutic effect on tumor cells.
Puerarin Protective effect on liver
Puerarin contains saponins, which can protect liver tissue from immune damage. Puerarin can protect liver injury through gastric absorption, induce activated hepatic stellate cell apoptosis, reverse chemically induced liver fibrosis, and protect acute liver injury induced by carbon tetrachloride. At the same time, puerarin has various physiological activities.
Puerarin Anti-arrhythmia, anti-angina
Studies have shown that puerarin can reduce the incidence of cardiac fibrillation in Kunming mice induced by chloroform, and significantly increase the threshold dose of cardiac arrest, ventricular presystole, ventricular fibrillation and ventricular tachycardia in SD rats induced by aconitine, indicating that puerarin is suitable for the treatment of arrhythmia. Puerarin injection is effective in the treatment of coronary heart disease angina pectoris. Its mechanism includes: firstly, it can reduce heart rate and blood pressure, improve vital signs, reduce myocardial oxygen consumption, expand coronary artery, improve myocardial hypoxia, ischemia and hemorheology indexes; Secondly, reducing blood viscosity has the effect of softening blood vessels, improving atherosclerosis, repairing vascular endothelial cells, and preventing disease deterioration. Studies have confirmed that the application of puerarin injection in the treatment of elderly patients with coronary heart disease and angina pectoris can not only improve the incidence, but also make blood vessels dilate, relieve hypoxia and ischemia, further improve blood rheology, muscle oxygen consumption index and other indicators, and the effect is ideal.
Puerarin Impact on cardiovascular system
Total flavonoids in Pueraria can increase blood flow in brain and coronary arteries. Puerarin can obviously promote brain circulation and peripheral circulation in animal and human.
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