Ekstrak Phellodendron pemasok Berberin pemasok Berberin ekstrak Phellodendron produsen Berberin ekstrak Phellodendron sampel gratis pabrik
Phellodendron Extract Berberine , is an important alkaloid extracted from coptis, Phellodendron and other plants.can inhibit dysentery bacillus, Escherichia coli, pneumococcus, Staphylococcus aureus, Streptococcus, Typhoid bacillus and amoeba.
Deskripsi
Phellodendron Extract Berberine HCL Introduction
Berberine HCL (Phellodendron Extract) was a is 5,6-dihdro-9,10-dimethoxy benzo-1,3-benzodioxolo {5,6-a} quinolizinium hydrochlorate dihydrate. The Phellodendron chinense Schneid. origin extracts contains not less than 97% alkaloids calculated on the anhydrous basis, it can be also extracted from Barberry Root,Coptis chinensis, even fibraureae stem origin.
Berberine hydrochloride, also known as berberine, is an important alkaloid extracted from coptis, Phellodendron and other plants.
Nama Produk | Ekstrak Phellodendron Berberin |
CAS No | 2086-83-1 |
Nama Latin | Cortex Phellodendri Chinensis |
Penampilan | yellow needle crystal powder |
Spesifikasi | 97% |
Pakage | 1kg/tas, 25kg/drum |
Penyimpanan | Atap yang lembap dan hindari penyimpanan yang terang dan tertutup rapat. |
Metode pengujian | Titration |
Mainly Specifications of Phellodendron Extract Berberine HCL
Berberine HCL Powder 97% Titration
Berberine HCL Granule 97% Titration
Benefits of Phellodendron Extract Berberine HCL
Phellodendron Extract Berberine can inhibit dysentery bacillus, Escherichia coli, pneumococcus, Staphylococcus aureus, Streptococcus, Typhoid bacillus and amoeba.
Clinical mainly used for intestinal infection and dysentery, also this product has good anti-arrhythmia effect.
Berberine has strong antitumor activity in vivo and in vitro and can induce the differentiation of B16 cells.
Medical Uses of Berberine Hydrochloride
Antioxidant Effect
Under normal circumstances, the body maintains a balance between antioxidants and pro-oxidants. Oxidative stress is a harmful process that may be an important mediator of damage to cellular structures, thereby inducing various disease states such as cardiovascular disease, cancer, neurological diseases, and diabetes. Overproduction of reactive oxygen species (ROS), most commonly through overstimulation of NADPH by cytokines or through the mitochondrial electron transport chain and xanthine oxidase, can lead to oxidative stress. Experiments have shown that berberine metabolites and berberine show excellent -OH scavenging activity, and their effects are roughly equivalent to the powerful antioxidant vitamin C. The increase in SOD (superoxide dismutase) activity and the decrease in MDA (a marker of lipid peroxidation) levels can be monitored by administering berberine to diabetic model rats . Further results showed that the scavenging activity of berberine is closely related to its ferrous ion chelating activity, and the C-9 hydroxyl group of berberine is an essential part.
Anti-tumor Effect
There have been numerous reports on the anti-cancer effects of berberine. Various studies in recent years have shown that berberine is effective in the adjuvant treatment of ovarian cancer, endometrial cancer, cervical cancer, breast cancer, lung cancer, colorectal cancer, kidney cancer, It is of great significance in the treatment of serious cancer diseases such as bladder cancer and prostate cancer . Berberine can inhibit the proliferation of tumor cells by interacting with various targets and mechanisms. It can change the expression of oncogenes and carcinogenesis-related genes to regulate the activity of related enzymes to inhibit proliferation .
Cardiovascular Effects
Berberine plays a pivotal role in the treatment of cardiovascular diseases and has an extremely wide range of applications. Berberine achieves the purpose of anti-arrhythmia by reducing the incidence of premature ventricular contractions and inhibiting the occurrence of ventricular tachycardia. Second, dyslipidemia is a major risk factor for cardiovascular disease and is characterized by increased levels of total cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL), and decreased levels of high-density lipoprotein (HDL), whereas berberine The stability of these indicators can be maintained extremely well. Long-term hyperlipidemia is an important cause of atherosclerotic plaque formation. It has been reported that berberine affects LDL receptors in liver cells to reduce human serum cholesterol levels in hepatocytes. Not only that, berberine has positive inotropic effects and has been used to treat congestive heart failure .
Endocrine Effects
Diabetes mellitus (DM) is a metabolic disorder characterized by an increase in blood glucose levels (hyperglycemia) resulting from the inability of pancreatic B cells to produce sufficient insulin, or the loss of effective target tissue responses to insulin. The hypoglycemic effects of berberine were discovered incidentally in the 1980s when treating diabetic patients with diarrhea.
Many Studies Show That Berberine Lowers Blood Sugar Through The Following Mechanisms:
Inhibits mitochondrial glucose oxidation and stimulates glycolysis, subsequently increasing glucose metabolism;
Reduced ATP levels by inhibiting mitochondrial function in the liver;
Inhibits the activity of DPP 4, a ubiquitous serine protease, thereby cleaving certain peptides that increase insulin levels in the setting of hyperglycemia.
Berberine has beneficial effects on improving insulin resistance and glucose utilization in tissues by reducing lipids (especially triglycerides) and plasma free fatty acid levels .
Typical Specification Sheet of Phellodendron Extract Berberine HCL 97%
Item Analisis | Spesifikasi | Metode |
Identifikasi | ||
Chemical reactions1 | A turbidity is produced immediately. | |
Chemical reactions 2 | A cherry- red color occurs. | |
IR | IR spectrum is concordant with spectrum of Berberine HCL RS. | |
Chloride reaction | The filtrate yields the reactions characteristic of chlorides. | |
Solubility | Dissolved in hot water, slightly soluble in water and ethanol, insoluble in ether. | |
Tes Bahan Aktif | ||
Berberine HCL (Dry basis) | ≥ 97.00 % | Titration |
Jateorhizine+Palmatine | ≤1.00% | HPLC |
Tes Fisik | ||
Penampilan | Yellow crystalline powder | Visual |
Bau & rasa | Karakteristik | Organoleptik |
Kepadatan massal | 0,3-0,45 g / mL | Ch.P 2020 IV<0993> |
Air | 8.00%-12.00% | Ch.P 2020 IV<0832> |
Residue on ignition | ≤0.20% | Ch.P 2020 IV<0841> |
Uji Kimia | ||
Logam Berat | ≤20.00ppm | Ch.P 2020 IV<0821> |
Pb | ≤3.00ppm | Ch.P 2020 IV<2321> |
Sebagai | ≤1.00ppm | Ch.P 2020 IV<2321> |
Cd (Kadmium) | ≤1.00ppm | Ch.P 2020 IV<2321> |
Hg<Total mercury> | ≤0.10ppm | Ch.P 2020 IV<2321> |
Tes Mikrobiologi | ||
Total Bacterial Counts | ≤1.000cfu/g | Ch.P 2020 IV<1105> |
Ragi dan Jamur | ≤100cfu / g | Ch.P 2020 IV<1105> |
E. Coli | Negatif dalam 1g | Ch.P 2020 IV<1106> |
Salmonella | Negatif dalam 10g | Ch.P 2020 IV<1106> |
Layanan Istirahat Tenang dengan Nilai Tambah Kami
>>> Backvita memiliki tenaga teknis profesional yang dapat memberikan dokumen dukungan teknis seperti: Standar, Spesifikasi, COA, MOA, MSDS,Diagram alir, Laporan, Kromatogram, Fakta Nutrisi, Uji stabilitas, dll.
>>> Kami berjanji untuk menyediakan layanan unik untuk memastikan Anda tidak perlu khawatir dalam pembelian dan penjualan produk.
>>> Tim analis data e-commerce global kami memiliki 10 tahun pengalaman dalam industri ekstrak tumbuhan. Mereka akan memberi Anda laporan data tentang negara-negara tempat produk Anda dijual untuk membantu Anda membuat keputusan yang tepat. Laporan data ini akan mencakup volume penjualan, saluran penjualan, analisis pesaing, dan informasi lainnya untuk membantu Anda lebih memahami permintaan dan tren pasar, sehingga dapat mengoptimalkan strategi pengadaan dan penjualan Anda.
>>> Selain laporan data, kami juga akan secara teratur memberi Anda informasi tentang produk yang sedang populer di pasar dan produk baru. Informasi ini akan membantu Anda mengikuti peluang dan tren potensial di pasar, serta membuat penyesuaian dan keputusan berdasarkan permintaan pasar.
>>> Jika Anda memiliki merek eksklusif Anda sendiri, kami juga akan menyediakan materi promosi dan poster untuk membantu Anda meningkatkan citra merek dan kesadaran pasar. Tim desain kami akan merancang materi promosi eksklusif untuk merek Anda sesuai dengan kebutuhan dan persyaratan Anda. Semua layanan bernilai tambah ini diberikan secara gratis kepada pelanggan mitra kami.
>>> Tujuan kami adalah untuk fokus pada pelanggan, menyediakan layanan tanpa rasa khawatir selama proses berlangsung, dan membantu Anda mencapai kinerja dan kesuksesan yang lebih baik.
>>> Jika Anda memiliki pertanyaan atau kebutuhan khusus tentang layanan bernilai tambah kami, jangan ragu untuk menghubungi kami. Kami akan melakukan yang terbaik untuk membantu Anda dan memastikan kepuasan Anda. Sekali lagi terima kasih atas dukungan dan perhatian Anda kepada kami, dan kami berharap dapat menjalin hubungan kerja sama jangka panjang dengan Anda.
Hubungi Kami
Dukungan Teknis
Dukungan Teknis Dasar
[Lembar Data Teknis]
[Sertifikat Disediakan]
[Laporan Residu Pelarut]
[Sertifikasi Pihak Ketiga]
[Laporan Residu Pestisida]
[Lembar Informasi Prosesi]
[Lembar Informasi Fakta Gizi]
[Laporan Uji Standar Mikrobiologi]
Dukungan teknis bernilai tambah