Effects of lutein and efficacy - Nutraceutical Ingredients and Cosmetic Raw Materials Supplier

Lutein, alias plant lutein, commonly known as “eye gold”, English name Lutein, molecular formula is C40H56O2, relative molecular weight is 568.85. Lutein looks golden yellow crystal, insoluble in water, easily soluble in oil and water after nano and microcapsule treatment.

It is usually found in vegetables with green leaves. Lutein is itself an antioxidant and absorbs harmful light such as blue light.

Co-existing with zeaxanthin in nature, it is the main component of plant pigments such as fruits, vegetables, corn and flowers. It is contained in the chloroplasts of leaves, and can transfer the absorbed light energy to chlorophyll a, which is speculated to have a certain protective effect on photooxidation and photodestruction. It is also the main pigment that makes up the macular region of the retina of the human eye.

Lutein is a nutrient that can be absorbed by human daily consumption of fruits and vegetables, but the absorption and utilization rate is generally low. If lutein is deficient, supplements can be taken. If you have an elderly person with a poor digestive system, you can use a spray under the tongue to supplement lutein. Lutein has been added as a dietary supplement since 1996. In addition, excessive absorption of lutein can cause excess burden on the liver, so the recommended dosage is about 12 mg per day.

The role of lutein 1:

Protect the eyes from light damage, delay the aging of the eyes and prevent lesions: ultraviolet and blue light in the sun into the eyes will produce a large number of free radicals, leading to cataracts, macular degeneration. Ultraviolet light can generally be filtered out by the cornea and lens of the eye, but blue light can penetrate the eye to the retina and macula, and lutein in the macula can filter out blue light to avoid blue light damage to the eye.

The role of lutein 2:

Vision protection: Lutein as an antioxidant and photoprotective effect, can promote the regeneration of Rhodopsin in retinal cells, can prevent high myopia and retinal detachment, and can improve vision and protect vision.

The role of lutein 3:

Avoid blue light on the eyes to relieve visual fatigue: lutein can quickly relieve visual fatigue, improve blurred vision, dry eyes, eye distension, eye pain, photophobia and other symptoms.

The role of lutein 4:

Improve macular pigment density: protect macula, promote macular development.

The role of lutein 5:

Prevent macular degeneration and retinitis pigmentosa; Reduce the occurrence of glass film warts, prevent AMD(age-related macular degeneration); Antioxidant helps prevent cardiovascular sclerosis, coronary heart disease and tumor diseases caused by aging

The efficacy of lutein

Antioxidant

Lutein has a strong antioxidant effect, which can inhibit the activity of reactive oxygen species and prevent the damage of reactive oxygen species to normal cells. Relevant experiments have proved that reactive oxygen species can react with DNA, proteins, lipids, weaken their physiological functions, and then lead to the occurrence of chronic diseases such as cancer, arteriosclerosis, age-related yellow devils degeneration. Lutein can inactivate singlet oxygen through physical or chemical quenching, so as to protect the body from damage and enhance the immune capacity of the body.

Reduce the incidence of cataracts

Cataract is the major eye disease leading to blindness worldwide. The latest research proves that increasing the intake of lutein can achieve the purpose of survival rate. It is believed that the mechanism is that lower macular pigment density is closely related to higher lens visual density in middle-aged and elderly people, while higher lens visual density is considered to be an obvious feature of cataract.

Delay arteriosclerosis

Recent studies have shown that lutein has a delayed effect on the early arteriosclerosis process. It is mainly the relationship between the thickness of arterial intima and the content of lutein in blood. The low content of lutein in blood is very likely to cause arterial wall thickening. With the gradual increase of lutein content, the trend of arterial wall thickening decreases, and arterial embolism is also significantly reduced. At the same time, Xanthoxylum in arterial wall cells can also reduce the oxidation of LDL cholesterol.

Anticancer

Many studies have shown that lutein has an inhibitory effect on a variety of cancers, such as breast cancer, prostate cancer, rectal cancer, skin cancer and so on. According to a recent study by the New York University School of Medicine, there is a strong relationship between reduced breast cancer incidence and lutein intake, and the study found that the experimental group with low lutein intake was more likely to have breast cancer than the group with high intake (2.08 to 2.21). This effect may involve indirect immunomodulatory effects in coordination with other organ tissues. The study concluded that taking lutein in the diet can not only inhibit tumorigenesis but even prevent tumorigenesis. It is recommended that 400 g to 600 g of fruit and vegetables per person per day can reduce the relative risk of cancer by 50%.

For retinal degeneration:

Retinitis pigmentosa (RP) is a chronic, progressive, hereditary, dystrophic retinitis pigmentosa. RP early only the symptoms of night blindness, does not affect the work, night blindness symptoms often appear in childhood, with the development of the disease, dark adaptability degradation, fear of light, vision quietly decline, vision narrowing, and finally a tubular vision and blindness, known as “not cancer cancer”. RP mainly includes primary retinitis pigmentosa, crystalline retinitis pigmentosa, white punctate retinitis pigmentosa and anopigmentosa. RP lesions are mainly the progressive degeneration of the upper cortex of the retinal nerve, especially the rod cells responsible for vision in dark light, the appearance of night blindness, followed by the gradual atrophy of various layers of the retina from the outside to the inside, accompanied by gliosis. The pigment epithelium also has denaturation and hyperplasia, and it can be seen that pigment loss or accumulation, and migration to the inner retina. The retinal blood vessel wall is thickened by hyaline degeneration, and even the lumen is completely occlusive. Choroidal vessels may have varying degrees of sclerosis, capillaries completely or partially disappeared. The optic nerve may be completely atrophied, and there is often gliosis on the optic rib, forming a membrane mass that connects with the glial membrane in the retina. The Harvard Eye Disease Case Management Group studied the relationship between age-related macular degeneration (AMD) and retinitis pigmentosa (RP) and lutein intake, and divided the patients into three groups, respectively, with 30mg, 10mg and 3mg of lutein intake per day. People who took 30mg of lutein daily for 140 days had an average increase of 20-40% in retinal pigment, and the visual acuity of patients with age-related macular degeneration (AMD) and retinitis pigmentosa (RP) lesions increased significantly. There was an 86% difference in treatment rates between the 30mg group and the 3mg group. It can be seen that lutein supplementation can increase the retinal pigment density, improve the vision of RP patients, and improve the treatment rate of RP.

Prevention and treatment of retinopathy and pigmentation

Lutein is the main component of macular pigment in the retina of human eye. Blue light has the highest energy in all visible light that can reach the retina, and has the strongest effect on macular damage, while lutein can play a role in filtering blue light. High energy blue light can also induce free radicals and damage optic nerve cells, while lutein can quench singlet oxygen and capture reactive oxygen species, playing an antioxidant role. Lutein can avoid the damage caused by blue light to the eyes, protect retinal tissue, improve vision, make vision more accurate, protect the retina, reduce the occurrence of cataracts, prevent retinitis pigmentation, zeaxanthin and lutein, highly concentrated in the macular area, that is, the part responsible for fine vision, the health care of the eyes is very important.

Prevention and treatment of macular disease

Western medicine treats macular degeneration mainly by laser therapy, fibrinolytic solvent, antiplatelet coagulant and lutein product improvement. These can treat existing new blood vessels and control the disease, but can not prevent the formation of new blood vessels, further absorption of blood stasis, restore vision, prevent repeated attacks, far less than the ideal treatment of traditional Chinese medicine, you can use laser and lutein products at the same time, as well as in the process of disease recovery, To strive for more opportunities to use Chinese medicine treatment to achieve the effect of both symptoms and root causes.

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