Curcumin

Anti-cancer and antioxidant-Turmeric Root Extract curcumin

If there’s one ingredient that’s as popular in the health supplement world as it is in the sports supplement industry, it’s curcumin! Although the curcumin ingredient is well known and it has been used in medical practice for centuries, scientific research is finally starting to catch up and dig deeper into the ultimate value of curcumin. Whether you’re a bodybuilder, weekend warrior, marathon runner or just an amateur weightlifter, it’s well known that too much inflammation can cause a lot of problems. However, it is important to note that not all inflammation is harmful, for example, resistance training causes an inflammatory response in muscles, which helps muscles repair and become stronger and larger. Another example is injury. Inflammation is a key physiological process that must occur for normal wound healing. But when your joints, tendons, or even your intestines become chronically inflamed, it’s time to take action. While there are a variety of ways to reduce inflammation, one of the most common is to take a supplement with a potent anti-inflammatory effect – curcumin.

curcumin

Curcumin is a very popular ingredient in the supplement industry. It has a wide range of benefits, but is primarily used to reduce inflammation. Curcumin is the main natural polyphenol found in turmeric, a root herb of the ginger family. [1]

Turmeric, it turns out, not only adds flavor to food, but also has many health benefits

Historically, turmeric (commonly known as turmeric) has been used to treat a variety of health conditions due to its anti-inflammatory, antioxidant, antibacterial, anti-cancer and anti-mutation properties. [1] The health benefits of turmeric are largely attributed to its curcumin content, which has been found to induce cell activity and target specific signaling molecules. [1]

Studies have shown that curcumin is beneficial for treating inflammation, metabolic syndrome, reducing pain, promoting kidney health, and helping to treat degenerative eye diseases. [1]

Studies have shown that curcumin is beneficial for treating inflammation, metabolic syndrome, reducing pain, promoting kidney health, and helping to treat degenerative eye diseases. [1]

Preliminary studies have shown that tetrahydrocurcumin is a stronger antioxidant, a more powerful blood sugar regulator, and is superior at optimizing blood lipid levels compared to its curcumin counterpart.

bioavailability

Since curcumin is rapidly metabolized in the body, [22] it makes sense that its effects could be attributed to one or more of its metabolites. However, given the exponential growth of science over the last half century or so, it’s also understandable that we’re not entirely sure what this fundamental building block is at first. Tetrahydrocurcumin was first discovered in 1978, [24] and was quickly labeled as a key bioactive metabolite of curcumin.

Studies have shown that tetrahydrocurcumin has strong biological activity compared with other metabolites of curcumin. [25] From a chemical perspective, 4-HC has also proven to be strong, and studies have found it to be more stable than curcumin in 0.1 phosphate buffers at pH 7.2 and 37 ° C.

Higher bioavailability and stronger antioxidant activity

Tetrahydrocurcumin: Better water solubility, better nitrogen, hydrogen, and LDL protection One study in this review found that because tetrahydrocurcumin is more water soluble than curcumin, it is more effective at inhibiting N2O induced H2O-induced lipid peroxidation. [26]

Tetrahydrocurcumin is colorless

Tetrahydrocurcumin is the main metabolic component of curcumin, and the compound is believed to have efficacy. From a structural point of view, tetrahydrocurcumin is very similar to curcumin, except that it has four extra hydrogen atoms. [2,3] Another major difference is color. Curcumin is known for its bright golden-orange hue, while tetrahydrocurcumin is colorless. [2, 3]

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Reference

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